anti trka pe Search Results


trka pe  (R&D Systems)
90
R&D Systems trka pe
p75 neurotrophin receptor (p75NTR) is expressed by and modulates the activity of human plasmacytoid dendritic cells (pDCs). (A) Expression of p75NTR and <t>TrkA</t> receptor by human pDCs (black line) compared with unstained control (filled gray). (B) p75NTR expression by primary human pDCs from three different donors (red, green, and blue lines; gray, unstained control). The graph summarizes p75NTR levels (17 donors). (C) IFNα secretion by pDCs (17 donors) stimulated with CpG ODN2216 in the presence of nerve growth factor (NGF). (D) IFNα secretion by ODN2216-stimulated pDCs (15 donors) in the presence of NGF and the p75NTR inhibitory peptide Pep5. (E) IFNα secretion by pDCs (12 donors), normalized to treatment with ODN2216 alone, and correlated with p75NTR cell-surface expression. (F) IFNα secretion by pDCs (17 donors), normalized to treatment with ODN2216 alone, and correlated with BDCA-2 cell-surface expression. (G) IL-6 secretion by pDCs (five donors) stimulated overnight with an FcεRIα-specific IgE-crosslinking antibody and incubated with increasing NGF concentrations. (H) IL-6 secretion by pDCs (eight donors), normalized to those of antibody treatment only, stimulated overnight with an FcεRIα-specific, IgE-crosslinking antibody in the presence of NGF (25 ng ml −1 ) and the p75NTR inhibitory peptide Pep5. (I) Cell proliferation of CD4 + T cells from four allergic donors cocultured with autologous pDCs in the absence or presence of the patient specific antigen and NGF. (J) Level of proinflammatory cytokines in coculture of three allergic donors as described in panel (I) . Data in panels (D,E,F–H) are shown as scatterplots, and the mean values are indicated by the short horizontal lines. Data in panels (C,I,J) are shown as scatterplots on log scale, and the mean log-values are indicated by the short horizontal lines. In panels (A,B) , representative images are shown. MFI, mean fluorescent intensity; * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.0001.
Trka Pe, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+trka+pe/Human+TrkA+PE-conjugated+Antibody/pmc05562693-119-9-10
Average 90 stars, based on 1 article reviews
trka pe - by Bioz Stars, 2026-10
90/100 stars
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phycoerythrin pe conjugated anti human trka mouse monoclonal antibody  (R&D Systems)
93
R&D Systems phycoerythrin pe conjugated anti human trka mouse monoclonal antibody
p75 neurotrophin receptor (p75NTR) is expressed by and modulates the activity of human plasmacytoid dendritic cells (pDCs). (A) Expression of p75NTR and <t>TrkA</t> receptor by human pDCs (black line) compared with unstained control (filled gray). (B) p75NTR expression by primary human pDCs from three different donors (red, green, and blue lines; gray, unstained control). The graph summarizes p75NTR levels (17 donors). (C) IFNα secretion by pDCs (17 donors) stimulated with CpG ODN2216 in the presence of nerve growth factor (NGF). (D) IFNα secretion by ODN2216-stimulated pDCs (15 donors) in the presence of NGF and the p75NTR inhibitory peptide Pep5. (E) IFNα secretion by pDCs (12 donors), normalized to treatment with ODN2216 alone, and correlated with p75NTR cell-surface expression. (F) IFNα secretion by pDCs (17 donors), normalized to treatment with ODN2216 alone, and correlated with BDCA-2 cell-surface expression. (G) IL-6 secretion by pDCs (five donors) stimulated overnight with an FcεRIα-specific IgE-crosslinking antibody and incubated with increasing NGF concentrations. (H) IL-6 secretion by pDCs (eight donors), normalized to those of antibody treatment only, stimulated overnight with an FcεRIα-specific, IgE-crosslinking antibody in the presence of NGF (25 ng ml −1 ) and the p75NTR inhibitory peptide Pep5. (I) Cell proliferation of CD4 + T cells from four allergic donors cocultured with autologous pDCs in the absence or presence of the patient specific antigen and NGF. (J) Level of proinflammatory cytokines in coculture of three allergic donors as described in panel (I) . Data in panels (D,E,F–H) are shown as scatterplots, and the mean values are indicated by the short horizontal lines. Data in panels (C,I,J) are shown as scatterplots on log scale, and the mean log-values are indicated by the short horizontal lines. In panels (A,B) , representative images are shown. MFI, mean fluorescent intensity; * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.0001.
Phycoerythrin Pe Conjugated Anti Human Trka Mouse Monoclonal Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+trka+pe/Human+TrkA+PE-conjugated+Antibody/10__1097_slash_cad__0b013e328364312f-71-5-12
Average 93 stars, based on 1 article reviews
phycoerythrin pe conjugated anti human trka mouse monoclonal antibody - by Bioz Stars, 2026-10
93/100 stars
  Buy from Supplier

Image Search Results


p75 neurotrophin receptor (p75NTR) is expressed by and modulates the activity of human plasmacytoid dendritic cells (pDCs). (A) Expression of p75NTR and TrkA receptor by human pDCs (black line) compared with unstained control (filled gray). (B) p75NTR expression by primary human pDCs from three different donors (red, green, and blue lines; gray, unstained control). The graph summarizes p75NTR levels (17 donors). (C) IFNα secretion by pDCs (17 donors) stimulated with CpG ODN2216 in the presence of nerve growth factor (NGF). (D) IFNα secretion by ODN2216-stimulated pDCs (15 donors) in the presence of NGF and the p75NTR inhibitory peptide Pep5. (E) IFNα secretion by pDCs (12 donors), normalized to treatment with ODN2216 alone, and correlated with p75NTR cell-surface expression. (F) IFNα secretion by pDCs (17 donors), normalized to treatment with ODN2216 alone, and correlated with BDCA-2 cell-surface expression. (G) IL-6 secretion by pDCs (five donors) stimulated overnight with an FcεRIα-specific IgE-crosslinking antibody and incubated with increasing NGF concentrations. (H) IL-6 secretion by pDCs (eight donors), normalized to those of antibody treatment only, stimulated overnight with an FcεRIα-specific, IgE-crosslinking antibody in the presence of NGF (25 ng ml −1 ) and the p75NTR inhibitory peptide Pep5. (I) Cell proliferation of CD4 + T cells from four allergic donors cocultured with autologous pDCs in the absence or presence of the patient specific antigen and NGF. (J) Level of proinflammatory cytokines in coculture of three allergic donors as described in panel (I) . Data in panels (D,E,F–H) are shown as scatterplots, and the mean values are indicated by the short horizontal lines. Data in panels (C,I,J) are shown as scatterplots on log scale, and the mean log-values are indicated by the short horizontal lines. In panels (A,B) , representative images are shown. MFI, mean fluorescent intensity; * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.0001.

Journal: Frontiers in Immunology

Article Title: Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells

doi: 10.3389/fimmu.2017.00981

Figure Lengend Snippet: p75 neurotrophin receptor (p75NTR) is expressed by and modulates the activity of human plasmacytoid dendritic cells (pDCs). (A) Expression of p75NTR and TrkA receptor by human pDCs (black line) compared with unstained control (filled gray). (B) p75NTR expression by primary human pDCs from three different donors (red, green, and blue lines; gray, unstained control). The graph summarizes p75NTR levels (17 donors). (C) IFNα secretion by pDCs (17 donors) stimulated with CpG ODN2216 in the presence of nerve growth factor (NGF). (D) IFNα secretion by ODN2216-stimulated pDCs (15 donors) in the presence of NGF and the p75NTR inhibitory peptide Pep5. (E) IFNα secretion by pDCs (12 donors), normalized to treatment with ODN2216 alone, and correlated with p75NTR cell-surface expression. (F) IFNα secretion by pDCs (17 donors), normalized to treatment with ODN2216 alone, and correlated with BDCA-2 cell-surface expression. (G) IL-6 secretion by pDCs (five donors) stimulated overnight with an FcεRIα-specific IgE-crosslinking antibody and incubated with increasing NGF concentrations. (H) IL-6 secretion by pDCs (eight donors), normalized to those of antibody treatment only, stimulated overnight with an FcεRIα-specific, IgE-crosslinking antibody in the presence of NGF (25 ng ml −1 ) and the p75NTR inhibitory peptide Pep5. (I) Cell proliferation of CD4 + T cells from four allergic donors cocultured with autologous pDCs in the absence or presence of the patient specific antigen and NGF. (J) Level of proinflammatory cytokines in coculture of three allergic donors as described in panel (I) . Data in panels (D,E,F–H) are shown as scatterplots, and the mean values are indicated by the short horizontal lines. Data in panels (C,I,J) are shown as scatterplots on log scale, and the mean log-values are indicated by the short horizontal lines. In panels (A,B) , representative images are shown. MFI, mean fluorescent intensity; * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.0001.

Article Snippet: Human cells were characterized using the antibodies as follows: TrkA-PE (R&D Systems); BDCA-2-FITC, BDCA-4-PE, p75NTR-APC, p75NTR-FITC, p75NTR-PE (Miltenyi Biotec); CD45-V500, CD3-PE, CD4-FITC, CD8-PerCP, FcεRIα-FITC, IL-3R-PE Cy7, CD184-PE Cy7, MHC-I-PE Cy7, MHC-II-PE, CD80-V450, CD86-PE, CD83-V500, OX40L-V500, PD-L1-PE Cy7, CCR7-V450, CCR9-APC (BD Biosciences), CD3-APC eFluor780, CD4-APC, CD8-PE Cy7, CD25-PE (eBioscience), and CD69-PerCP Cy5.5 (BioLegend).

Techniques: Activity Assay, Expressing, Control, Incubation